Trialkylamine Hydrochloride

Trialkylamine Hydrochloride

Trialkylamine Hydrochloride is a premium organic ammonium salt engineered for high-performance applications as a phase-transfer catalyst (PTC), acid scavenger, and reactive intermediate in fine chemical and pharmaceutical manufacturing.

  • Product Introduction

Trialkylamine Hydrochloride | Custom Synthesis & Industrial Grade Supplier:

Product Overview & Market Positioning

Trialkylamine Hydrochloride is a premium organic ammonium salt engineered for high-performance applications as a phase-transfer catalyst (PTC), acid scavenger, and reactive intermediate in fine chemical and pharmaceutical manufacturing. Synthesized via precise neutralization of high-purity tertiary amines with anhydrous hydrogen chloride under strict stoichiometric control, this material excels in multiphase reaction systems. By efficiently facilitating reactant transfer across immiscible liquid-liquid or liquid-solid phases, it significantly reduces reaction cycles and improves overall yields in complex alkylation and substitution processes.
Available for global export, our product line supports both bulk industrial operations and highly regulated cGMP pharmaceutical synthesis paths.

 

Product Specifications & Analytical Methods:
Typical values determined via internal quality control and third-party analytical verification.

Specification Parameter

Target Value / Limit

Test Method

Assay (Titration)

>= 99.0% (Synthesis Grade)

>= 98.0% (Industrial Grade)

Non-aqueous Acid-Base Titration

Appearance

White to off-white crystalline powder or flakes

Visual Inspection

Moisture (Karl Fischer)

<= 0.5% (General)

<= 0.3% (Ultra-low moisture variant)

USP / ISO 760

Free Amine Content

<= 0.3%

Gas Chromatography (GC)

Residue on Ignition (Ash)

<= 0.1%

Gravimetric Analysis

Melting Point Range

Specific to alkyl chain distribution (+/- 2 deg C)

Capillary Melting Point

 

Chemical & Physical Properties:
CAS Registry: Variable depending on specific alkyl chain configuration (e.g., Trioctylamine HCl: CAS 60522-35-6; generalized tertiary amine hydrochloride structures available).
Molecular Formula: [R3NH]+Cl- (where R typically represents C6 to C10 alkyl chains).
Solubility: Soluble in chlorinated solvents, aromatic hydrocarbons, and alcohols; insoluble in water.
Thermal Stability: Stable up to 150 deg C under an inert atmosphere; sensitive to strong oxidizing agents and high-temperature moisture exposure.

 

Key Applications:
Phase-Transfer Catalysis (PTC): Accelerates heterogeneous reactions involving anions (such as cyanations, oxidations, and alkylations) by effectively solubilizing inorganic salts into organic phases.
Acid Scavenging: Neutralizes byproduct hydrogen chloride generated during acylation and condensation reactions, mitigating reactor corrosion and preventing side-chain degradation.
Metal Extraction & Hydrometallurgy: Operates as an extractant carrier in liquid-liquid extraction setups for recovering rare earth and transition metals from acidic leach solutions.
Surfactants & Intermediates: Serves as a fundamental chemical precursor for specialized quaternary ammonium compounds and cationic surfactants.

 

Pharmaceutical Manufacturing Relevance:
Deployed in strict compliance with current Good Manufacturing Practice (cGMP) auxiliary chemical standards, this product is heavily utilized in the synthesis of complex API intermediates. Strict upper limits on residual heavy metals and isomeric impurities are standard. Furthermore, a tightly controlled free-amine profile (<= 0.3%) minimizes interference during downstream coupling reactions, effectively reducing batch failure rates across multi-step organic synthesis pathways.

 

Grade & Quality Offerings:
Industrial Grade (>= 98.0% Purity): Optimized for bulk surfactant production, mineral extraction, and general industrial-scale synthesis.
Synthesis Grade (>= 99.0% Purity): Features ultra-low moisture (<= 0.3%) and a tightly controlled heavy metal profile tailored for fine chemicals and pharmaceutical intermediates. Custom assay adjustments are supported.

 

Quality Control & Traceability:
Every commercial lot undergoes rigorous multi-parameter screening prior to release. In-house testing utilizes calibrated gas chromatography (GC), Karl Fischer moisture titrators, and automatic melting point apparatuses. Retained samples from all batches are archived for a minimum of 36 months to ensure complete traceability. Pre-shipment verification through independent third-party laboratories (such as SGS or Intertek) can be arranged for bulk orders.


Technical Documentation:
Certificate of Analysis (COA): Provided per batch, detailing actual assay, moisture, and impurity test profiles. [Download Sample COA PDF]
Safety Data Sheet (SDS): Comprehensive hazard identification, safe handling instructions, and transport classification (UN number details). [Download SDS PDF]
Technical Data Sheet (TDS): Complete summary of physical constants, recommended storage parameters, and handling guidelines. [Download TDS PDF]

 

Packaging, Storage & Shelf Life
Standard Packaging: 25 kg fiber drums with inner polyethylene liners; 200 kg steel-plastic composite drums for bulk formats. Custom multi-wall paper bags are available upon volume agreement.
Storage Conditions: Store in a cool, dry, well-ventilated area away from direct sunlight, moisture, and strong oxidizing agents. Keep containers hermetically sealed to prevent atmospheric moisture absorption.
Shelf Life: 24 months from the date of manufacture under recommended storage conditions.

 

Supply Chain & Procurement Terms
Minimum Order Quantity (MOQ): 100 kg for standard R&D evaluation; 1 metric ton for commercial bulk delivery.
Sample Policy: 100 g to 500 g analytical samples are available for laboratory evaluation. Shipping costs apply based on destination and hazardous material classifications.
Lead Time: 7 to 10 business days for stocked items; 3 to 4 weeks for custom synthesis or bulk production runs exceeding 5 metric tons.
Bulk Supply Capacity: Annual supply agreements supported with scheduled monthly or quarterly shipments to stabilize market volatility and ensure uninterrupted production.

 

OEM & Custom Specifications
Our custom manufacturing infrastructure accommodates specific alkyl chain distributions, tailored moisture thresholds, and specialized particle size reduction (milling and sieving). Analytical testing methods can be co-developed or cross-validated against client-specific internal standards prior to contract execution.

 

FAQ:

Q: What is the typical shelf life if a drum is opened?

A: Once opened, the material should be consumed immediately or resealed under an inert nitrogen blanket to prevent moisture pick-up from the atmosphere.

Q: Is this product classified as hazardous for transport?

A: Yes. Depending on the exact alkyl chain length, it typically falls under corrosive or miscellaneous hazardous material classifications. Refer to Section 14 of the SDS for precise UN shipping names and hazard classes.

Q: Can you provide customized particle size distribution?

A: Yes, mechanical milling can be applied to meet specific dissolution rate requirements in organic solvents.

 

Request a Quotation:
To receive a formal commercial quotation including current freight rates, volume-tiered pricing, and lead time verification, submit your volume requirements and target destination through our inquiry form or contact our sales engineering team directly at Kelvinsong1982@yimingbiotech.com.cn

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