Propylene Glycol

Propylene Glycol (USP/EP/Industrial Grade):

Propylene Glycol (1,2-propanediol) is a clear, viscous, colorless, and hygroscopic synthetic liquid with the chemical formula CH3CH(OH)CH2OH. Manufactured via the catalytic hydration of propylene oxide, our high-purity production lines yield low-congener profiles essential for regulated formulation sectors. It functions as an effective solvent, humectant, coupling agent, and intermediate across diverse industrial chemical processes. Standard production utilizes petrochemical pathways via propylene oxide hydration; bio-based (glycerin-derived) and ISCC-certified sustainable alternatives are available upon request to meet strict corporate ESG and carbon-reduction mandates.

 

Product Specifications:

Parameter	USP Grade	Industrial Grade	Test Method
Purity (Min %)	99.8%	99.5%	GC (Gas Chromatography)
Water Content (Max %)	0.2%	0.3%	Karl Fischer Titration
Specific Gravity (20/20 °C)	1.035 - 1.037	1.035 - 1.039	ASTM D891
Distillation Range (°C)	185 - 189	182 - 190	ASTM D1078
Color (APHA, Max)	10	15	ASTM D1209
Residue on Ignition (Max %)	0.005%	0.01%	USP / ASTM D2192
Chloride (Max ppm)	1.0	5.0	Turbidimetric Method
Sulfate (Max ppm)	5.0	20.0	Turbidimetric Method

 

Chemical & Physical Properties:

CAS Number	57-55-6
Molecular Weight	76.09 g/mol
Boiling Point	187.4 °C (760 mmHg)
Flash Point	99 °C (Closed Cup)
Viscosity	48.1 mPa·s at 20 °C
Solubility	Miscible in all proportions with water, acetone, and chloroform.

 

Applications:

Pharmaceuticals: Active ingredient solvent, plasticizer in capsule manufacturing, and humectant in topical ointments.
Cosmetics & Personal Care: Moisture-retaining agent in toothpastes, skin lotions, deodorants, and shampoos.
Food & Beverage: Solvent for food colorings and flavorings, humectant for pet food and confections.
Industrial & HVAC: Base fluid for secondary coolants, industrial heat transfer systems, deicing fluids, and unsaturated polyester resins.

 

Pharmaceutical Manufacturing Relevance:

Meeting United States Pharmacopeia (USP) and European Pharmacopoeia (EP) specifications, this grade satisfies strict regulatory thresholds for residual solvents and heavy metals. Controlled synthesis parameters prevent diethylene glycol (DEG) cross-contamination, ensuring gas chromatography limits remain strictly below 0.1%. Trace element limits comply with ICH Q3D guidelines, minimizing validation burdens during drug product dossier submissions and streamlining vendor audits.

 

Grade & Quality Requirements

USP / EP Grade: Meets current monographs for pharmaceutical and high-end personal care applications. Kosher, Halal, and EXCIPACT GMP-certified options available.
Industrial Grade: Optimized for chemical synthesis, antifreeze formulations, and resin production, minimizing cost without compromising technical thresholds.

 

Quality Control:

Every production lot undergoes rigorous testing via gas chromatography (GC) and Karl Fischer titration prior to release. Retention samples are securely stored for 24 months in temperature-controlled facilities. All analytical instruments are calibrated daily against NIST-traceable standards to eliminate measurement drift.

 

Technical Documents

COA (Certificate of Analysis): Lot-specific analytical data supplied with every shipment, verifying compliance with stated specifications.
SDS (Safety Data Sheet): Comprehensive hazard identification, handling protocols, and emergency response data compliant with GHS standards.
TDS (Technical Data Sheet): Detailed physical properties, recommended handling temperatures, and storage guidelines.

 

Packaging & Storage:

Packaging Options:

l215 kg net weight internally coated epoxy-phenolic steel drums.

l1,000 kg Intermediate Bulk Containers (IBC / Tote tanks).

lISO tank containers for bulk deliveries.

Storage Conditions: Store in tightly sealed containers in a cool, dry, well-ventilated area away from strong oxidizing agents. Being a hygroscopic material, nitrogen blanketing is recommended for long-term bulk storage to prevent moisture absorption.

 

Supply & Procurement：

MOQ (Minimum Order Quantity): 1 pallet (4 × 215 kg drums or 1 × 1,000 kg IBC).

Sample Policy: 500 ml laboratory samples available for analytical verification (freight collect or pre-paid per agreement).

Lead Time: 7 to 14 business days for standard stock items from regional warehouses; 30 to 45 days for direct port shipments.

Commercial & Trade Terms: Flexible international trade terms supported, including FOB, CIF, CFR, and DDP options depending on the destination port and regional distribution hubs.

Bulk Supply: Annual volume contracts with scheduled rolling forecasts and fixed pricing mechanisms supported by dedicated regional logistics.

 

OEM & Custom Specifications：

Custom packaging options include private labeling, tamper-evident seals, customer-specified drum markings, and customized Certificate of Analysis formatting to integrate directly with enterprise resource planning (ERP) incoming inspection portals.

 

 

Request a Quote：
Please specify the required grade, volume, destination port or zip code, packaging preference, and preferred Incoterms to receive a formal commercial offer within 24 business hours.

 

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