Boiling Point: 82.5 deg C (180.5 deg F) at 760 mmHg
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Melting Point: -88.5 deg C (-127.3 deg F)
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Flash Point: 12 deg C (53.6 deg F) [Closed Cup]
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Vapor Pressure: 4.4 kPa at 20 deg C
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Refractive Index (n_D^20): 1.376 - 1.378
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Miscibility: Fully miscible in water, ethanol, ether, and chloroform at 20 deg C.
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CAS Number: 67-63-0
Molecular Formula: C3H8O
Molecular Weight: 60.10 g/mol
EINECS Number: 200-661-7
HS Code: 2905.12.2000
|
Parameter |
Specification Limit |
Test Method |
|
Assay (Purity) |
>= 99.9% (wt/wt) |
ASTM D1252 / GC |
|
Water Content |
<= 0.05% (wt/wt) |
ASTM E1064 (Karl Fischer) |
|
Specific Gravity (20/20 deg C) |
0.785 - 0.787 |
ASTM D4052 |
|
Color (Platinum-Cobalt) |
<= 5 |
ASTM D1209 |
|
Residue on Evaporation |
<= 0.001% (g/100mL) |
ASTM D1353 |
|
Acidity (as Acetic Acid) |
<= 0.002% |
ASTM D1613 |
|
Boiling Point |
82.5 deg C (180.5 deg F) at 760 mmHg |
|
Melting Point |
-88.5 deg C (-127.3 deg F) |
|
Flash Point |
12 deg C (53.6 deg F) [Closed Cup] |
|
Vapor Pressure |
4.4 kPa at 20 deg C |
|
Refractive Index (n_D^20) |
1.376 - 1.378 |
|
Miscibility |
Fully miscible in water, ethanol, ether, and chloroform at 20 deg C. |
API Crystallization & Purification:
Utilized as a recrystallization solvent for active pharmaceutical ingredients due to its favorable partition coefficients and low boiling point, facilitating rapid solvent stripping.
Cleanroom & Equipment Sanitization:
Deployed for surface wipe-downs and equipment flushing in ISO Class 5-8 cleanrooms; evaporates completely without leaving surfactant residues.
Chromatography & Analytical Testing:
Serves as an organic modifier and mobile phase component in High-Performance Liquid Chromatography (HPLC) assays.
Electronics Surface Preparation:
Applied in defluxing and cleaning semiconductor sub-assemblies where trace metallic contaminants must remain below 0.1 ppm.
Pharmaceutical Manufacturing Relevance
ICH Q3C (R8) Compliance:
Residual solvent profiles align strictly with Class 3 guidelines, permitting controlled usage limits in drug product formulations without toxicological safety justification concerns.
GMP Alignment:
Synthesized, handled, and packaged in facilities operating under current Good Manufacturing Practice principles, ensuring full batch segregation and traceability.
Low Bioburden Profile:
Produced via high-temperature distillation loops that eliminate microbial contaminants prior to sub-micron membrane filtration (0.2 um) at the filling stage.
USP / EP Monograph Alignment:
Meets or exceeds current United States Pharmacopeia (USP) and European Pharmacopoeia (EP) specifications for Isopropyl Alcohol.
Heavy Metal Thresholds:
Total heavy metals (as Lead) maintained at < 1 ppm, verified via Inductively Coupled Plasma Mass Spectrometry (ICP-MS).
Non-Volatile Residue Control:
Monitored continuously to prevent silicone or plasticizer leaching from transfer lines into the final packaged solvent.
In-Process Monitoring: Inline refractometers and automated densitometers monitor purity parameters during fractional distillation.
Pre-Shipment Retention: Retained samples from every production lot are archived in climate-controlled lockers for 24 months to support post-market traceability audits.
Third-Party Verification: Random lots are independently analyzed by ISO/IEC 17025 accredited laboratories to validate internal gas chromatography calibration curves.
Access lot-specific compliance data instantly for internal quality assurance and regulatory review boards:
COA (Certificate of Analysis):
Each shipment includes a lot-specific COA detailing exact assay values, water content percentage, specific gravity, and acidity levels measured prior to dispatch. -> [Request Sample Batch COA]
SDS (Safety Data Sheet):
Compliant with OSHA 29 CFR 1910.1200 and GHS standards. Details flash point parameters, personal protective equipment (PPE) requirements, spill containment procedures, and UN 1219 transport classifications. -> [Download GHS SDS (PDF)]
TDS (Technical Data Sheet):
Comprehensive parameter breakdown, storage stability data, and compatibility guidelines available for download in PDF format. -> [Download Technical Data Sheet (PDF)]
Packaging & Storage
Packaging Options:
Steel Drums: 160 kg net weight, interior coated with phenolic epoxy resin to prevent iron pickup.
IBC Totes (Intermediate Bulk Containers): 800 kg net weight, food-grade HDPE with integrated bottom discharge valves and tamper-evident seals.
ISO Tanks: Bulk delivery ranging from 20 to 25 metric tons for high-volume continuous processing plants.
Storage Conditions: Store in a dedicated, grounded, explosion-proof flammable liquids warehouse. Maintain ambient temperatures between 15 deg C and 30 deg C. Keep containers tightly sealed under a dry nitrogen blanket to prevent atmospheric moisture absorption.
Shelf Life: 24 months from the date of manufacture when stored in unopened, original containers.
Bulk Supply Stability:
Backed by steady feedstock allocation agreements (propylene/acetone pathways) ensuring zero production curtailment across multi-year contracts.
Sample Availability:
500 mL glass bottle samples provided to qualified industrial procurement teams for laboratory evaluation and incoming quality verification. Freight costs apply. -> [Order Laboratory Sample]
MOQ (Minimum Order Quantity):
1 pallet (4 x 160 kg drums / 640 kg) for drum shipments; 1 IBC tote (800 kg) for intermediate orders; 1 ISO tank for bulk orders.
Lead Time:
Ex-stock standard inventory: Dispatched within 5 to 7 business days from port of loading.
Annual supply contracts: Scheduled quarterly shipments managed via rolling forecasts.
Purity Tuning:
Custom fraction cuts available for buyers requiring specific water content thresholds (<= 0.02%) or specialized trace-metal constraints.
Private Labeling:
Custom drum stenciling, laser-etched lot coding, and client-specific COA formatting available for large-scale distribution partners.
Container Customization:
Compatibility adjustments for specific valve materials (PTFE / Viton gaskets) upon request.
To receive a formal commercial quotation including freight rates (FOB/CIF terms), current volume pricing tiers, and the latest batch COA, submit your procurement requirements through our inquiry portal or contact our chemical sales desk directly. -> [Submit RFQ / Contact Chemical Desk]
As one of the most professional industrial chemicals manufacturers and suppliers in China, we're featured by quality products and good service. Please feel free to buy high-grade industrial chemicals from our factory. For price consultation, contact us.
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